Do you train hard and have the proper diet but still are not satisfied with the mass and definition of your muscles?
Supplement LEUCINE – it is almost certain that this is the compound that is deficient in your muscles!
Leucine is an amino acid with an anabolic activity affecting the development of lean muscle mass through multiple metabolic mechanisms:
Leucine closely cooperates with the most important anabolic hormones: insulin, GH, IGF and – probably – testosterone.
It is a very potent stimulator of the insulin production and release, comparable to glucose which was considered, until recently, the most potent activator of this hormone.
As a compound with certain properties of a fatty substance, it reduces the barrier between the fatty and aqueous phase of cellular membranes and facilitates the transport of amino acids and energy compounds to the muscle cells, in which process it closely cooperates with insulin.
At the same time – owing to the abovementioned features – it easily penetrates into muscle cells itself and is one of three amino acids – along with isoleucine and valine – which freely enter into muscle cells.
Inside these cells, it plays the role of an ingredient for building muscle proteins and structures participating in the anabolism stimulation by hormones called “leucine locks”, and also limits the activity of catabolic enzymes, destroying muscle proteins.
The most important mechanism of its anabolic activity is based on the cooperation with insulin, GH, IGF and – probably – testosterone. The three former hormones do not directly stimulate protein production, i.e. strength and mass development, but act on this process through anabolic enzymes called kinases. Kinases control the two most important stages of protein synthesis - transcription and translation. Although testosterone – as a steroid hormone – directly stimulates protein production at the stage of transcription, the current studies suggest that kinases may support or even replace such hormones in their anabolic activity.
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This product was added to our catalog on Friday 19 September, 2008. |
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